Cxbladder Triage 膀胱癌篩查檢測

Cxbladder Triage 是一種非侵入性的分子診斷測試，旨在協助臨床醫生排除膀胱癌，為您和您的患者提供更大的安心。

Cxbladder Triage 的設計目的是利用專有算法結合表型和基因型因素，通過分離指數 ‘G+P INDEX’ 來識別患有尿路上皮癌 (UC) 機率低的患者。使用 G+P INDEX，Cxbladder Triage 專注於準確識別患有血尿且 UC 機率低的患者，這些患者可能不需要進行更廣泛的評估。

Cxbladder Triage 已在一項包含 587 名出現肉眼血尿患者的臨床研究中得到驗證。該研究顯示，Cxbladder Triage 的敏感性為 95.1%，且具有 98.5% 的高陰性預測值，40% 的患者被準確地分流為 UC 機率低。Cxbladder Triage 尤其適合對出現血尿的低風險患者進行分流[1]。

Cxbladder Triage is a non-invasive molecular diagnostic test to assist clinicians in ruling out bladder cancer – giving you and your patients greater peace of mind.

Cxbladder Triage is designed to identify patients with a low probability of having urothelial carcinoma (UC) using a proprietary algorithm combining both phenotypic and genotypic factors into a segregation index – ‘the G+P INDEX’. Using the G+P INDEX, Cxbladder Triage focuses on accurately identifying patients with hematuria who have a low probability of UC, for whom a more extensive evaluation may not be required.

Cxbladder Triage has been validated in a clinical study with 587 patients presenting with gross hematuria. With a sensitivity of 95.1% and high negative predictive value of 98.5%, the study showed that 40% of patients were accurately triaged out with a low probability of UC. Cxbladder Triage is particularly appropriate for triaging low risk patients presenting with hematuria[1].

Reference:

[1] Kavalieris et al: ‘A segregation index combining phenotypic (clinicalcharacteristics) and genotypic (gene expression) biomarkers from a urinesample to triage-out patients presenting with hematuria who have a lowprobability of urothelial carcinoma. BMC urology 2015; 15:23.